The plastic nature of the vascular wall: a continuum of remodeling events contributing to control of arteriolar diameter and structure.

Metalloproteinases, Mechanical Factors and Vascular Remodeling

Chronic increases in arterial blood flow elicit an adaptive response of the arterial wall, leading to vessel enlargement and reduction in wall shear stress to physiological baseline value. Release of nitric oxide from endothelial cells exposed to excessive shear is a fundamental step in the remodeling process, and potentially triggers a cascade of events, including growth factor induction and m...

Vascular remodeling arterioles: plasticity of the vessel wall.

In the recent review by Martinez-Lemus et al. (10) on the plastic nature of the vascular wall, they hypothesize that a remodeling continuum exists that allows the media to rapidly modify its structural characteristics, specifically through the repositioning of smooth muscle cells (SMC). It was suggested that such a system of remodeling contributes to the active control of vascular diameter and ...

Luis A . Martinez - Lemus , Michael A . Hill and Gerald A . Meininger Diameter and Structure Remodeling Events Contributing to Control of Arteriolar

بررسی ارتباط اتصالات میواندوتلیال، میان سلول های اندوتلیال و نظم مارپیچی سلولهای عضلانی صاف جدار شرایین توزیع کننده (عضلانی)

Background and Purpose: Conventionally, the architecture of the artery wall is based upon the close-packed smooth muscle cells, endothelial and adventitial cells in both sides of internal elastic lamina (IEL). However, the adventitia and endothelium are now viewed as key players in vascular growth and repair. Recent work raises fundamental questions about the cellular heterogeneity of arterie...

The Plastic Nature of the Vascular Wall: A Continuum

hemodynamics has been considered to occur either through short-term vasomotor responses or in the longer term via adaptive structural changes. Such adaptations of the vessel wall include structural remodeling, rarefaction, collateralization, and even angiogenesis. A newly emerging concept of plasticity of the vascular wall, however, is blurring the boundaries between these previously distinct p...